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Navojoa is the fourth-largest city in the northern Mexican state of Sonora and is situated in the southern part of Sonora, 608 kilometers (360 miles) south of the state's border with the U.S. state of Arizona. It is the administrative seat of a large municipality, located in the Mayo Valley.

Navojoa has many hotels with a range of cost and quality. Most hotels are located off Pesqueira Street, mainly between the 1-km-long area between Tecnologico Avenue and Centenario Boulevard.

The "Museo Regional del Mayo" (Mayo's Regional Museum) is located in the former railroad station building opposite Santa Fe Springs square. The Museum has 5 rooms which exhibit temporary paint, handicraft and sculpture expositions, pre-hispanic and colonial objects, ethnographic expositions dedicated to the Mayos' culture and other objects related to Navojoa's history.

The Tehuelibampo Museum is an eco-museum with 89 petroglyphics carved in the stones over 500 years ago by the Mayo people. It is located next to the Mayo river, some kilometers north-west of Navojoa.

The city is near the Gulf of California which offers a variety of beaches. The surrounding country is also popular for hunting ducks, doves and deer.

Las Bocas, 30 miles south of Navojoa, is a small beach community on the Gulf of California that is frequently visited by the local residents of Navojoa during spring. (April-May). It is particularly popular during "Semana Santa" (Holy Week), when campers stay for seven days and then return to Navojoa for Easter celebrations.

Many people from Navojoa own a second house in Las Bocas.

The Adolfo Ruiz Cortines Dam, also called Mocuzarit, is a popular fishing spot and stores water used for irrigating the valley via the Mayo River. Other uses include kayaking, geoglyph-viewing and other leisure activities.

Navojoa also acts as a hub for those visiting the colonial town of Alamos, which is 48 kilometers (30 miles) inland toward the mountains of the Sierra Madre.